Don't worry, nothing to be concerned about if you have a jailbroken iDevice. Your should be safe to connect and sync if you please, just don't update your firmware by "Accident". There has been no word of any issues blocking DFU mode restores, at this point in time.
Apple has released iTunes 10.1.1, an updated to iTunes 10.1 which was released in mid-November, of which now includes some bug fixes for the NVIDIA GeForce 9400 and 9600 video card on macs, not to mention a fix for those that were having issues syncing music videos.
Quote:
This release provides a number of important bug fixes, including:
- Addresses an issue where some music videos may not play on Macs equipped with NVIDIA GeForce 9400 or 9600